MCQ QUIZ on HISTORY OF MICROBIOLOGY
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MCQ.1. According to Pasteur statements which one of the following is true
a. Living organisms discriminate between stereoisomers
b. Fermentation is a aerobic process
c. Living organisms doesn’t discriminate between stereoisomers
d. Both a and b
MCQ.2. “I found floating therin earthly particles, some green streaks, spirally wound serpent-wise, and orderly arranged, the whole circumstance of each of these streaks was abut the thickness of a hair
on one’s head”…. These words are of
a. Leeuwenhoek b. A. Jenner
c. Pasteur d. Koch
MCQ.3. The principle light- trapping pigment molecule in plants, Algae, and cyanobacteria is
a. Chlorophyll a
b. Chlorophyll b
c. Porphyrin
d. Rhodapsin
MCQ.4. During Bio Geo chemical cycle some amount of elemental carbon was utilized by the microorganisms. The phenomenon is called as
a. Dissimilation
b. Immobilization
c. Decomposition
d. Neutralization
MCQ.5. Who demonstrated that open tubes of broth remained free of bacteria when air was free of dust.
a. Abbc Spallanzani
b. John Tyndall
c. Francisco Redi
d. Pasteur
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MCQ.6. Reverse isolation would be appropriate for
a. a patient with tuberculosis
b. a patient who has had minor surgery
c. a patient with glaucoma
d. a patient with leukemia
MCQ.7. The symptome “ general feeling of illness and discomfort “ is called
a. Cystitis
b. Malaise
c. Anaphylactic shock
d. Arthritis
MCQ.8. On soybean which of the following forms symbiotism
a. Azatobactor paspali
b. Rhizobium
c. Nostoc
d. Bradyrhizobium
MCQ.9. Who provide the evidence that bacteriophage nucleic acid but not protein enters the host cell during infection
a. Alfred D.Hershey & Leonard Tatum in 1951.
b. Alfred D.Hershey & Zindar Lederberg in 1951.
c. Alfred D.Hershey & Martha Chase in 1952.
d. Alfred D.Hershey & Macleod in 1952.
MCQ.10. Spirulina belongs to
a. Xanthophyceae
b. Cyanophyceae
c. Rhodophyceae
d. Pheophyceae
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MCQ.11. The first antibody to contact invading microorganisms was
a. IgG
b. IgM
c. IgA
d. IgD
MCQ.12. The light emitted by luminescent bacteria is mediated by the enzyme
a. Coenzyme Q
b. Luciferase
c. Lactose dehydrogenase
d. Carboxylase reductase
MCQ.13. Pick out the vector using in human Genome project
a. Phagemid vector
b. Yeast artificial chromosomes
c. Cosmid vectors
d. Yeast episomal plasmids
MCQ.14. Salt and sugar preserve foods because they
a. Make them acid
b. Produce a hypotonic environment
c. Deplete nutrients
d. Produce a hypertonic environment
MCQ.15. In a fluorescent microscope the objective lens is made of
a. Glass
b. Quartz
c. Polythene
d. None of these
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MCQ.16. Fixation of atmospheric nitrogen is by means of
a. Biological process
b. Lightining
c. Ultraviolet light
d. All of the above
MCQ.17. Which one of the following fungi is the most serious threat in a bone marrow transplant unit?
a. Candida albicans
b. Aspergillus
c. Blastomyces
d. Cryptococus
MCQ.18. Direct microscopic count can be done with the aid of
a. Neuberg chamber
b. Anaerobic chamber
c. Mineral oil
d. Olive oil
MCQ.19. The image obtained in a compound microscope is
a. Real
b. Virtual
c. Real inverted
d. Virtual inverted
MCQ.20. Enzymes respons ib le for a lcoho l ic fermentation
a. Ketolase
b. Zymase
c. Peroxidase
d. Oxidase
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MCQ.21. Which type of spores are produced sexually?
a. Conidia
b. Sporangiospores
c. Ascospores
d. None of these
MCQ.22. Bacterial transformation was discovered by
a. Ederberg and Tatum
b. Beadle and Tatum
c. Griffith
d. None of these
MCQ.23. Father of microbiology is
a. Louis Pasteur
b. Lister
c. A.V. Leeuwenhock
d. Robert Koch
MCQ.24. The antiseptic method was first demonstrated by
a. Lwanowski
b. Lord Lister
c. Edward Jenner
d. Beijerinck
MCQ.25. Small pox vaccine was first discovered by
a. Robert Koch
b. Louis Pasteur
c. Lister
d. Edward Jenner
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MCQ.26. The term mutation was coined by
a. Pasteur
b. Darwin
c. Hugo devries
d. Lamark
MCQ.27. Compound microscope was discovered by
a. Antony von
b. Pasteur
c. Johnsen & Hans
d. None of these
MCQ.28. Father of Medical Microbiology is
a. Pasteur
b. Jenner
c. Koch
d. A.L.Hock
MCQ.29. Disease that affects many people at different countries is termed as
a. Sporadic
b. Pandemic
c. Epidemic
d. Endemic
MCQ.30. Prophylaxis of cholera is
a. Protected water supply
b. Environmental sanitation
c. Immunization with killed vaccines
d. All of these
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MCQ.31. In electron microscope, what material is used as an objective lense?
a. Magnetic coils
b. Superfine glass
c. Aluminium foils
d. Electrons
MCQ.32. The main feature of prokaryotic organism is
a. Absence of locomotion
b. Absence of nuclear envelope
c. Absence of nuclear material
d. Absence of protein synthesis
MCQ.33. The stalked particles on the cristae of mitochondria are called
a. Glyoxysomes
b. Peroxisomes
c. Oxysomes
d. Spherosomes
MCQ.34. Antiseptic methods were first introduced by
a. Lord Lister
b. Iwanowski
c. Beijernick
d. Edward Jenner
MCQ.35. Kuru disease in Humans is caused by
a. Bacteria
b. Viroides
c. Prions
d. Mycoplasma
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MCQ.36. A mutation that produces termination codon is
a. Mis-sense mutation
b. Neutral mutation
c. Non-sense mutation
d. Reverse mutation
MCQ.37. During conjunction the genetic material will be transferred through
a. Cell wall
b. Medium
c. Pili
d. Capsule
MCQ.38. Antiseptic surgery was discovered by
a. Joseph Lister
b. Ernest Abbe
c. Pasteur
d. Beijerink
MCQ.39. Tuberculosis is a
a. Water borne disease
b. Air borne disease
c. Food borne disease
d. Atthropod borne disease
MCQ.40. Phagocytic phenomenon was discovered by
a. Louis Pasteur
b. Alexander Fleming
c. Metchnikof
d. Robert Koch
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MCQ.41. Meosomes are also known as
a. Mitochondria
b. Endoplasmic reticulum
c. Plasmids
d. Chondroids
MCQ.42. Hybridoma technique was first discovered by.
a. Kohler and Milstein
b. Robert Koch
c. ‘D’ Herelle
d. Land Steiner
MCQ.43. The m in imum number of bacter ia required to produce clinical evidence of death in a susceptible animal under standard condition is called
a. LD50
b. ID
c. MLD
d. All of these
MCQ.44. In Electron Microscope source of electrons is from
a. Mercury lamp
b. Tungsten metal
c. both a and b
d. None of these
MCQ.45. Griffith (1928) reported the phenomenon of transformation first in
a. H. influenzae
b. Bacillus species
c. Pneumococci
d. E.coli
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MCQ.46. The resolution power of the compound microscope is
a. 0.2 micron
b. 0.2 millimeter
c. 0.2 Angstrom units
d. 0.2 centimeter
MCQ.47. The capacity of a given strain of microbial species to produce disease is known as
a. Pathogen
b. Virulence
c. Infection
d. None of these
MCQ.48. Monoclonal antibodies are associated with the name of
a. Burnet
b. Medwar
c. Milstein kohler
d. Owen
MCQ.49. Lederberg and Tatum (1946) described the phenomena of
a. Conjunction
b. Transformation
c. Mutation
d. Plasmids
MCQ.50. Hanging drop method for motility study was first introduced by
a. Robert Koch
b. Louis Pasteur
c. Jenner
d. Leeuwenhock
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MCQ.51. Electron microscope gives magnification upto
a. 100 X
b. 2000 X c. 50,000 X
d. 2,00,000 X
MCQ.52. Term vaccine was coined by
a. Robert Koch
b. Pasteur
c. Needham
d. None of these
MCQ.53. The inventor of Microscope is
a. Galileo
b. Antony von
c. Pasteur
d. Koch
MCQ.54. First Pasteur conducted fermentation experiments in
a. Milk
b. Food material
c. Fruit juices
d. Both a and c
MCQ.55. Modern concepts of chemotherapy was proposed by
a. Paul Ehrlich
b. Joseph Lister
c. Elie Metchnikoff
d. None of these
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MCQ.56. The role of phagocytosis was discovered by
a. Paul Ehrlich
b. Joseph lister
c. Elie Metchikoff
d. Pasteur
MCQ.57. L – forms are discovered by
a. Klein Berger
b. Louis Pasteur
c. Robert Koch
d. Antony von Leeuwenhock
MCQ.58. The causative organism of rocky mountain spotted fever was first described by
a. Howard Ricketts
b. da Rocha-lima
c. Both a and b
d. Robert Koch
MCQ.59. The term bacteriophage was coined by
a. De’Herelle
b. F.W. Twort
c. Beijernick
d. Jwanosky
MCQ.60. Viral infection of bacteria was discovered by
a. De’Herelle
b. F.W. Twort
c. Beijernick
d. Jwanoksy
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MCQ.61. Eye cannot resolve any image less than
a. 1ìm
b. 2ìm
c. 7ìm
d. 5ìm
MCQ.62. Compound Microscope was discovered by
a. A.V. Lewenhoek
b. Pasteur
c. Janssen and Hans
d. None of these
MCQ.63. Electron Microscope was discovered by
a. Prof. Fritz
b. Janssen and Hans
c. Knoll and Ruska
d. None of these
MCQ.64. Magnification range of light microscope is
a. 1000x – 5000x
b. 1000x – 2000x
c. 500x – 1000x
d. None of these
MCQ.65. Condensation of light in light Microscope is by
a. Objective
b. Condensor
c. Ocular
d. All of these
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MCQ.66. Light gathering capacity of Microscope is called
a. Numerical aperture
b. Angular aperture
c. Both a and b
d. None of these
MCQ.67. If 10x and 40x objectives are used (air is the medium), the numerical aperture is
a. 1.5
b. 2.0
c. 1.0
d. 1.8
MCQ.68. The ability of Microscope to distinguish two objects into two separate objects, is called.
a. Resolving power
b. Wave length
c. N.A.
d. None of these
MCQ.69. Limit of resolution of compound microscope is
a. 0.018 Ao
b. 0.1 mm
c. 5 ìm
d. 1 mm
MCQ.70. Source of light in fluorescence microscopy is from
a. Mercury lamp
b. Sunlight
c. Both a and b
d. None of these
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MCQ.71. Who perfected a magnetic lens in 1927
a. Gabor
b. Broglie
c. Busch
d. None of these
MCQ.72. The magnefication power of electron microscope developed by Knell and Ruska is
a. 10,000x
b. 12,000x
c. 15,000x
d. 20,000x
MCQ.73. In electron microscope source of electrons is from
a. Mercury lamp
b. Tungsten metal
c. Both a and b
d. None of these
MCQ.74. The e lectron passed out from the specimen are called
a. Primary electrons
b. Secondary electrons
c. Tertiary electrons
d. None of these
MCQ.75. Mycorrhiza was first observed by
a. Funk
b. Frank
c. Fisher
d. Crick
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MCQ.76. The transfer of genetic material during transformation is proved basing on Griffith’s experiment by
a. Avery Macleod & Mc.Carthy
b. Lederberg & Taulum
c. Zinder & Lederberg
d. Watson & Crick
MCQ.77. Phagocytic theory was proposed by
a. Louis Pasteur
b. Elie Metchnikoff
c. Behring
d. Widal
MCQ.78. Anaphylaxia was first observed by
a. Parter & Richet
b. Coombs
c. Gell
d. None of these
MCQ.79. Primary mediators in anaphylaxis
a. Histamine
b. Seratonin
c. Heparin
d. All of these
MCQ.80. Arthus reaction was discovered by
a. Marrice Arthus
b. Von Perquit
c. Richet
d. Porter
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MCQ.81. Serum sickness reaction was discovered by
a. Marrice Arthus
b. Von perquit
c. Richet
d. Porter
MCQ.82. Hybridoma technique was developed by
a. Kochler & Milston
b. Niel’s Jerne
c. Both a and b
d. None of these
MCQ.83. Disease that effects many people at different countries is termed as
a. Sporadic
b. Pandemic
c. Epidemic
d. Endemic
MCQ.84. If the vectors transmit the infection mechanically they are called
a. Biological vectors
b. Mechanical vectors
c. Biological reservoir
d. Both a and c
MCQ.85. If a person can be infected by direct contact with infected tissue of another person, it is termed as
a. Indirect contact transmission
b. Attachment
c. Direct contact transmission
d. None of these
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MCQ.86. Reduction of virulence is known as
a. Exaltation
b. Attenuation
c. Both a and b
d. None of these
MCQ.87. Enhancement of virulence is known as
a. Exaltation
b. Attenuation
c. Both a and b
d. None of these
MCQ.88. The virulence of a pathogen is usually measured by
a. LD
b. MLD
c. ID
d. All of the above
MCQ.89. The lethal dose required to kill 50% of the lab animals tested under standard called
a. ID
b. LD50
c. ID50
d. MLD
MCQ.90. The most important virulence factors are
a. Adhesions
b. Invasiveness
c. Toxigenicity
d. Enzymes
e. All of the above
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MCQ.91. The ability of a pathogen to spread in ths host tissues after establishing the infection is known as
a. Adhesion
b. Invasiveness
c. Toxigenicity
d. None of these
MCQ.92. Which is the following enzyme acts as a spreading factor?
a. Hyaluronidase
b. Coagulase
c. Catalase
d. DNase
MCQ.93. Vibrio Cholerae was discovered by
a. Koch
b. Metchnikoff
c. John Snow
d. Virchow
MCQ.94. E.coli was first isolated by
a. Louis Pasteur
b. Escherich
c. Shiga
d. Robert Koch
MCQ.95. Mycobacterium tuberculosis was first discovered by
a. Robert Koch
b. Edward Jenner
c. Louis Pasteur
d. None of these
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MCQ.96. Mycobacterium lepree was discovered by
a. Robert Koch
b. Hansen
c. Edward Jenner
d. Louis Pasteur
MCQ.97. Streptococcus pneumoniae was isolated by
a. Robert Koch
b. Edward Jenner
c. Antony von Leewenhock
d. Louis Pasteur
MCQ.98. B.anthracis was isolated by
a. Louis Pasteur
b. Robert Koch
c. Antonyvon Leewenhok
d. None of these
MCQ.99. Staphylococcus aureus was isolated by
a. Rosenbach
b. Louis Pasteur
c. Passet
d. Sir Alexander Ogston
MCQ.100. Pseudomonas aeruginosa was first named
a. Schroeter and Gessard
b. Robert Koch
c. Louis Pasteur
d. Edward Jenner
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